Response to letter regarding article, "Cardiac magnetic resonance imaging: a new gold standard for ventricular volume quantification during high-intensity exercise".
نویسندگان
چکیده
BACKGROUND Accurate measures are critical when attempting to distinguish normal from pathological changes in cardiac function during exercise, yet imaging modalities have seldom been assessed against invasive exercise standards. We sought to validate a novel method of biventricular volume quantification by cardiac MRI (CMR) during maximal exercise. METHODS AND RESULTS CMR was performed on 34 subjects during exercise and free-breathing with the use of an ungated real-time (RT-ungated) CMR sequence. ECG and respiratory movements were retrospectively synchronized, enabling compensation for cardiac cycle and respiratory phase. Feasibility of RT-ungated imaging was compared with standard exercise CMR imaging with ECG gating (gated); accuracy of RT-ungated CMR was assessed against an invasive standard (direct Fick); and reproducibility was determined after a second bout of maximal exercise. Ventricular volumes were analyzed more frequently during high-intensity exercise with RT-ungated compared with gated CMR (100% versus 47%; P<0.0001) and with better interobserver variability for RT-ungated (coefficient of variation=1.9% and 2.0% for left and right ventricular stroke volumes, respectively) than gated (coefficient of variation=15.2% and 13.6%; P<0.01). Cardiac output determined by RT-ungated CMR proved accurate against the direct Fick method with excellent agreement (intraclass correlation coefficient, R=0.96), which was highly reproducible during a second bout of maximal exercise (R=0.98). CONCLUSIONS When RT-ungated CMR is combined with post hoc analysis incorporating compensation for respiratory motion, highly reproducible and accurate biventricular volumes can be measured during maximal exercise.
منابع مشابه
Cardiac Magnetic Resonance Imaging: A New Gold Standard for Ventricular Volume Quantification During High-Intensity Exercise La Gerche et al: Exercise Cardiac Magnetic Resonance
متن کامل
The Correlation between Left and Right Ventricular Ejection Fractions in Patients with Ischemic Heart Disease, Documented by Cardiac Magnetic Resonance Imaging
Introduction: The correlation between right and left ventricular ejection fractions (RVEF and LVEF, respectively) has been studied in only a small number of patients with a marked decrease in RVEF and LVEF. The aim of the present study was to compare LVEF and RVEF in patients with ischemic heart disease. RVEF and LVEF were measured by Cardiovascular Magnetic Resonance (CMR) imaging. Materials a...
متن کاملResponse by Bohm et al to Letter Regarding Article, "Right and Left Ventricular Function and Mass in Male Elite Master Athletes: A Controlled Contrast-Enhanced Cardiovascular Magnetic Resonance Study".
Circulation. 2016;134:e364–e365. DOI: 10.1161/CIRCULATIONAHA.116.024362 e364 Philipp Bohm, MD Wilfried Kindermann, MD Tim Meyer, MD Jürgen Scharhag, MD In Response: We agree with Heidbuchel and colleagues that our findings do not clearly refute the concept of exercise-induced right ventricular (RV) damage because no prospective longitudinal study has been performed so far. However, our finding ...
متن کاملModerate intensity supine exercise causes decreased cardiac volumes and increased outer volume variations - a cardiac magnetic resonance imaging study
Background The effects on left and right ventricular (LV, RV) volumes during physical exercise remains controversial. Furthermore, no previous study has investigated the effects of exercise on longitudinal contribution to stroke volume (SV) and the outer volume variation of the heart. The aim of this study was to determine if LV, RV and total heart volumes (THV) as well as cardiac pumping mecha...
متن کاملPseudo-CT Generation from Magnetic Resonance Imaging by fuzzy look up table algorithm
Introduction: Despite growing interest in the use of magnetic resonance imaging (MRI) in the external radiotherapy design process (RT), Computer Tomography (CT) remains a gold standard and is regarded as a basic imaging modality in radiotherapy. MRI shows the high contrast in soft tissues without any radiation exposure to patients. As a result, MRI is used in functional tissue ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation. Cardiovascular imaging
دوره 6 2 شماره
صفحات -
تاریخ انتشار 2013